Substrate-Chromogens for Immunohistochemistry


Published by: moser495, Wed Jan 24 2024

Substrate-Chromogens for Immunohistochemistry

CD BioSciences, a US-based biotechnology company focusing on the development of imaging technology, has announced the launch of its innovative line of Chromogenic Substrates for immunohistochemistry (IHC). These cutting-edge substrates offer superior signal sensitivity, long-term storage stability, enhanced safety, and user-friendliness, empowering researchers to unlock deeper insights into protein expression and function within tissues. Immunohistochemistry is the study of the localization, characterization, and relative quantification of peptides and proteins in tissue cells using the antigen-antibody reaction, in which an antigen specifically binds to an antibody and a chemical reaction results in the visualization of dyes such as fluorescein and other chromogens, as well as enzymes, metal ions and isotopes, and other chemicals that label the antibody. IHC has a wide range of applications. For instance, it is widely used to diagnose abnormal cells, such as those found in cancerous tumors, by using specific molecular markers to characterize specific cellular events, such as proliferation or cell death (apoptosis). Additionally, IHC is widely used to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of biological tissues. Recognizing the wide range of applications for IHC, CD BioSciences has developed a variety of chromogenic substrates, each with high signal sensitivity, to provide customers with a research tool that is stable for long-term storage, sensitive, safe and easy to use. For example, the HRP Blue Plus Substrate-Chromogen Kit (Catalog NO: SCI020108) is designed for use with peroxidase detection systems and allows the detection of cellular antigens or nucleic acids in paraffin-embedded tissues, cryostat sections, cytosmears, and cell preparations.

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www.bioimagingtech.com/substrate-chromogens-for-immunohistochemistry.html





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